60-year-old female with recurrent vaginal cancer after chemoradiotherapy. A complete pelvic exenteration with ileostomy and end-colostomy were performed. The patient experienced several post-surgical complications (depicted by arrows in axial contrast-enhanced CT images, (A-F): right hydroureteronephrosis due to reflux from the ileal conduit (A), dehiscence of the anterior abdominal wall with protrusion of small bowel loops (B), perineal fluid collection (C), bowel anastomosis dehiscence with contrast extravasation into a pelvic collection (D), pelvic hematoma (E), and chronic osteomyelitis of the left pubic bone (F).