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Microbiota dysbiosis in early-life alters serum metabolome(a) volcano plot showing differential metabolites in amp-treated and van-treated mice. N = 9–10/group. Criteria for significant differences (VIP > 1, P < 0.05 and fold change ≥ 2). (b) heatmap of representative differential metabolites. The metabolites derived from the gut bacteria were marked with “#”. *P < 0.05, **P < 0.01.
