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. 2022 Jul 25;37(1):2063–2077. doi: 10.1080/14756366.2022.2103552

Table 7.

Physicochemical properties of the tested compounds passed Lipinski and Veber Rules

Comp. Lipinski Rules
Veber Rules
Num HD Num HA M Wt AlogP Num Rotatable Bonds TPSA
12a 2 4 395.475 3.685 6 109.53
12b 2 4 429.92 4.35 6 109.53
12c 2 4 409.501 4.171 6 109.53
12d 2 4 383.464 3.214 6 109.53
12e 2 4 417.909 3.879 6 109.53
12f 2 4 397.491 3.701 6 109.53
12g 2 5 433.48 3.843 7 118.76
12h 2 5 467.925 4.508 7 118.76
12i 2 5 447.506 4.33 7 118.76
12j 2 4 437.899 4.524 6 109.53
12k 2 4 472.344 5.189 6 109.53
12l 2 4 451.925 5.01 6 109.53
13a 3 5 446.478 3.117 7 138.63
13b 3 5 480.923 3.781 7 138.63
13c 3 5 460.505 3.603 7 138.63