Table 7.
Comp. | Lipinski Rules |
Veber Rules
|
||||
---|---|---|---|---|---|---|
Num HD | Num HA | M Wt | AlogP | Num Rotatable Bonds | TPSA | |
12a | 2 | 4 | 395.475 | 3.685 | 6 | 109.53 |
12b | 2 | 4 | 429.92 | 4.35 | 6 | 109.53 |
12c | 2 | 4 | 409.501 | 4.171 | 6 | 109.53 |
12d | 2 | 4 | 383.464 | 3.214 | 6 | 109.53 |
12e | 2 | 4 | 417.909 | 3.879 | 6 | 109.53 |
12f | 2 | 4 | 397.491 | 3.701 | 6 | 109.53 |
12g | 2 | 5 | 433.48 | 3.843 | 7 | 118.76 |
12h | 2 | 5 | 467.925 | 4.508 | 7 | 118.76 |
12i | 2 | 5 | 447.506 | 4.33 | 7 | 118.76 |
12j | 2 | 4 | 437.899 | 4.524 | 6 | 109.53 |
12k | 2 | 4 | 472.344 | 5.189 | 6 | 109.53 |
12l | 2 | 4 | 451.925 | 5.01 | 6 | 109.53 |
13a | 3 | 5 | 446.478 | 3.117 | 7 | 138.63 |
13b | 3 | 5 | 480.923 | 3.781 | 7 | 138.63 |
13c | 3 | 5 | 460.505 | 3.603 | 7 | 138.63 |