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. 2022 Jul 13;13:911381. doi: 10.3389/fimmu.2022.911381

Figure 4.

Figure 4

Dietary resveratrol supplementation alleviated the oxidative stress (induced by tBHP) induced depression ovarian oxidative stress and apoptosis-related pathway (Exp. 1). (A) Ovarian apoptosis-related gene expression. (B) Oxidative stress-related pathway (Nrf2-ARE) gene expression. (C) SIRT1-FoxO1/P53 gene expression. (D) Western-blot result of cell apoptosis-related pathway. (F-G) The immunofluorescence results of SIRT1 protein. Data are plot individual values (n = 10). CON, control; OS, oxidative stress (injection of 800 μmol/kg BW of tBHP); OSR, CON + 600 mg/kg resveratrol; SIRT1, silent information regulator 1; FoxO1, forkhead Box O1; Nrf2, nuclear factor E2-related factor 2. Statistical significance was evaluated by Tukey’s Test, p < 0.05.