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. 2022 Jul 13;13:911381. doi: 10.3389/fimmu.2022.911381

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Copyright © 2022 Wang, Jia, Celi, Zhuo, Ding, Zeng, Bai, Xu, Yin, Lv and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Dietary resveratrol supplementation alleviated the oxidative stress (by tBHP) induced changes in serum metabolites (Exp.1). (A, B) The principal component analysis (PCA) of the serum metabolites between OS vs. CON (A), and between OSR vs. OS group (B). (C, D) KEGG pathway enrichment of target metabolites between OS vs. CON (C), and between OSR vs. OS group (D). (E) Spearsman correlations between metabolites and cecum microbiota. Statistical significance was evaluated by the Student’s T-test, * p < 0.05.