Table 3.
Prognostic performance of models
| Model | Primary cohort | Internal Validation cohort | External Validation cohort | ||||||
|---|---|---|---|---|---|---|---|---|---|
| C index (95% CI) | P value | AIC | C index (95% CI) | P value | AIC | C index (95% CI) | P value | AIC | |
| Radiomics model | 0.75 (0.71–0.80) | Reference | 575 | 0.73 (0.69–0.78) | Reference | 602 | 0.71 (0.66–0.76) | Reference | 665 |
| Clinical-pathologic model | 0.72 (0.67–0.76) | <0.01* | 612 | 0.71 (0.67–0.73) | <0.01* | 645 | 0.70 (0.65–0.74) | <0.05* | 689 |
| AJCC TNM (eighth edition) | 0.65 (0.60–0.70) | <0.001* | 683 | 0.64 (0.59–0.68) | <0.001* | 712 | 0.63 (0.58–0.66) | <0.001* | 745 |
| Radiomics signature | 0.71 (0.66–0.74) | <0.01* | 655 | 0.70 (0.64–0.74) | <0.01* | 684 | 0.69 (0.63–0.72) | <0.01* | 703 |
AIC, Akaike information criteria; TNM, tumor node metastasis.