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. 2022 Jul 11;13:881359. doi: 10.3389/fimmu.2022.881359

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Copyright © 2022 Xiao, Wang, Liu, Liu, Yi and Hu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) GSVA analysis (B) Spearman correlation analysis between the signature and six immune cells (B cell, Macrophage, Myeloid dendritic cell, Neutrophil cell, T cell CD4+ T cell CD8+) ; (C) The comparison of PDCDl, PDCD1LG2, LAG3, HAVCR2, CD274,IDO1 and CTLA-4 expression levels between high-risk and low-groups; (D) Relationships between risk score and MSI. (E) Relationships between risk score and TMB. (F, G) The waterfall plot of somatic mutation landscape between two risk groups, ranked by top 20 frequently mutated genes.