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. 2021 Dec 9;2021:9305277. doi: 10.1155/2021/9305277

Table 2.

Table showing HEPA 1-6 tumour infiltrating immune cells after completion of ICI treatment. Data are shown as mean%of cells ± S.D. and are separated into control, treatment responders (TR), and treatment nonresponders (TNR) and are representative of n = 5 − 10 mice/group, P < 0.05; ∗∗P < 0.01, comparing TR to TNR.

Immune cell subsets associated with HEPA 1-6 tumours
CD3+ % of CD45+ CD4+ % of CD3+ CD4+ Treg % of CD4+ GZB+ NK+ % of NK+
Control 30.10 ± 1.17 19.85 ± 2.50  5.17 ± 1.27  8.39 ± 1.90 
TR αPD1 40.80 ± 6.43 18.18 ± 1.81 2.18 ± 0.61 11.92 ± 1.22
αCTLA4 43.95 ± 3.76 31.78 ± 4.62 2.71 ± 0.45 15.50 ± 2.81
αPD1 + αCTLA4 41.56 ± 5.42 33.35 ± 3.01 2.11 ± 0.28 16.08 ± 1.04∗∗
TNR 30.98 ± 1.54 23.68 ± 2.16 5.02 ± 1.47 8.74 ± 1.02