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. 2019 Oct 29;51(2):271–280. doi: 10.1111/apt.15555

Figure 2.

Figure 2

Proportion of patients in (A) the tofacitinib maintenance remitter dose de‐escalation and (B) the tofacitinib maintenance failure dose escalation subpopulations with clinical response, mucosal healing and remission over time in OCTAVE Open (non‐responder imputation). Data were based on local read of endoscopy. Missing data were imputed using non‐responder imputation; patients were treated as nonresponders after the time of discontinuation up to the visit they would have reached if they had stayed in the study. No imputation for missing data was applied for ongoing patients. N, number of evaluable patients