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. 2020 May 5;35(9):1660–1667. doi: 10.1002/jbmr.4028

Table 1.

Baseline Characteristics in the 365 Days Before the Index Hip of Patients Who Received Pharmacologic Treatment for Osteoporosis at 3 Months from Index Date

Characteristics Treated (n = 6938) Untreated (n = 24,027) Total (n = 30,965) p Value
N % N % N
Sociodemographics
Sex Women 6097 87.9 17,508 72.9 23,605 0.000
Men 841 12.1 6519 27.1 7360
Age (years) 65–74 1053 15.2 3061 12.7 4114 0.000
75–84 3557 51.3 10,354 43.1 13,911
≥85 2328 33.6 10,612 44.2 12,940
Mean (SD) 81.9 (6.5) 83.4 (7.0) 83.1 (6.9) 0.000
Use of health services
Primary care visits 0–4 2644 38.1 10,008 41.7 12,652 0.000
5–12 2912 42.0 9855 41.0 12,767
13 1382 19.9 4164 17.3 5546
ER visits 0–1 4408 63.5 15,413 64.2 19,821 0.348
≥2 2530 36.5 8614 35.9 11,144
Hospital admission Yes 1302 18.8 5006 20.8 6308 0.000
No 5636 81.2 19,021 79.2 24,657
Polypharmacy 0–5 3289 47.4 12,782 53.2 16,071 0.000
6–12 3592 51.8 11,126 46.3 14,718
≥13 57 0.8 119 0.5 176
Mean (SD) 5.88 (4.3) 4.74 (4.4) 4.99 (4.4) 0.000
Comorbidities
Previous fracture 1734 25.0 4959 20.6 6693 0.000
Osteoporosis 1717 24.8 2424 10.1 4141 0.000
Parkinson’s 408 5.9 1523 6.3 1931 0.165
Dementia 1445 20.8 6677 27.8 8122 0.000
Diabetes 2030 29.3 7710 32.1 9740 0.000
Rheumatoid arthritis 322 4.6 642 2.7 964 0.000
Stroke 687 9.9 3118 13.0 3805 0.000
Myocardial infarction 778 11.2 3209 13.4 3987 0.000
Heart failure 750 10.8 3092 12.9 3842 0.000
Depression 1492 21.5 4468 18.6 5960 0.000
Cancer 975 14.1 3851 16.0 4826 0.000
Malnutrition 98 1.4 434 1.8 532 0.026
Medication use
Opioid treatment 2482 35.8 6021 25.0 8503 0.000
Hypnotic treatment 1204 17.4 4233 17.6 5437 0.611
Oral corticoids 794 11.4 2261 9.4 3055 0.000
Antipsychotics 1112 16.0 4570 19.0 5682 0.000
Anxiolytics 3409 49.1 10,503 43.7 13,912 0.000
Antiarrythmics 325 4.7 117 4.9 1495 0.526
Antihypertensive treatment 5255 75.7 17,612 73.3 22,867 0.000
Diuretic treatment 2330 33.6 8201 34.1 10,531 0.395
Osteoporosis treatment 3805 54.8 1453 6.1 5258 0.000

ER = emergency room.