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. 2022 Jul 27;13(5):515–523. doi: 10.6004/jadpro.2022.13.5.5

Table 2. Interventions for Cancer-Related Fatigue.

Assessment Use of a valid, reliable screening tool for cancer-related fatigue
Identify treatable contributing factors, such as:

  • Pain

  • Emotional distress

  • Anemia

  • Sleep disturbance

  • Nutritional status

  • Activity level

  • Medication side effects

  • Alcohol or substance abuse

  • Comorbid conditions
Pharmacologic interventions Methylphenidate
Dexamethasone
Nonpharmacologic interventions Exercise

  • Moderate to vigorous activity, as tolerated

  • Strength training

  • Stretching and flexibility exercises

  • Avoid exercising one to two days after chemotherapy or if experiencing neutropenia, low platelet counts, anemia, or fevers


Nutrition

  • Nutrition consultation

  • Manage nausea or vomiting


Psychosocial interventions

  • Provide education about cancer-related fatigue

  • Energy conservation and pacing activities


Optimize sleep

  • Sleep hygiene, such as establishing routine, avoiding caffeine or alcohol near bedtime

  • Avoid long naps in the afternoon


Relaxation techniques

  • Progressive muscle relaxation

  • Guided imagery

  • Meditation

  • Massage

  • Healing touch

  • Journaling

  • Yoga

  • Music

Note. Information from McQuestion (2021); NCCN (2021).