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. 2022 Jul 27;17(7):e0271996. doi: 10.1371/journal.pone.0271996

Table 3. Moderating variables on within-subject associations between acute stressors or stress and cortisol.

Current cortisol levels Awakening response of cortisol1 Diurnal cortisol slope2 AUC cortisol Single day-time levels of cortisol (e.g. at wake up, in evening)
/ Ref. / Ref. / Ref. / Ref. / Ref.
Sociodemographic variables (BS)
• Age - - [93] - - [107] - - [107] - - [106]
• Gender (female vs. male) [87, 93, 96] - - - - - [103, 117]
• Socioeconomic status - - [88]
Health-related variables (BS)
• Mental disorders - [87, 98, 134] - - [124]
• Having a sibling with psychotic disorders - - [75]
• Spinal cord injury - - [79]
• 22q11.2 deletion syndrome - - [92]
• Higher activation of the normal X chromosome when having a premutation of FMR1 - [135]
Personality-related variables (BS)
• Coping - - [78]
• Trait anxiety - - [89]
Family-related variables (BS)
• Chronic caregiving stress - - [112, 113] - - [112] - - - - - [114]
• Parental warmth - - - - - [129] - - [103]
• Marital satisfaction - - - - [115]
• Family conflict and lack of parental affection during childhood - - [129]
Family-related variables (WS)
• Providing support to parents - - [132]
Subjective responses to stress (WS)
• Self-oriented thoughts - - [97]
• Past-oriented thoughts - - [97]
• Positive thoughts - - [97]
• Negative affect - - [97]
• Arousal - - [97]
• Coping - [78, 97]
• Rumination - - [111] - - [111] - - [111]
Other variables (BS)
• Life satisfaction - - [95]
• Previous negative life events - - [104]
• Satisfaction with network support - - [119]
• Believing in incremental theory of intelligence - - [86]
• Ethnic-racial identity - - [99] - - [99] - [99, 131] - - [99]
Other variables (WS)
• Time of the day - - [93]
• Performing volunteer work - - [128]
• Social contacts - [82]

BS = between-subject moderating variables; Ref. = References; WS = within-subject moderating variables; / = no moderation effect; ↑ = higher levels of moderating variable increased relationship between acute stress and cortisol (i.e. increased stress reactivity); ↓ = higher levels of moderating variable decreased relationship between acute stress and cortisol (i.e. decreased stress reactivity);

1 ↑ = higher levels of moderating variable was associated with increased cortisol awakening response, ↓ = higher levels of moderating variable was associated with decreased cortisol awakening response;

2 ↑ = higher levels of moderating variable was associated with a flatter diurnal cortisol slope, ↓ = higher levels of moderating variable was associated with steeper diurnal cortisol slope.