TABLE 3.
Exposure‐response relationship in RCC patients depending on whether or not dose intervention was advised, implemented and/or successful
| Number of patients | Percentage | PFS in weeks (median (range)) | P value | ||
|---|---|---|---|---|---|
| Dose adjustment advised | No | 18 | 35 | 22 (3‐208) | 0.307 |
| Yes | 33 | 65 | 30 (2‐264) | ||
| Dose intervention implemented | No | 10 | 30 | 18 (2‐168) | 0.288 |
| Yes | 23 | 70 | 44 (3‐264) | ||
| Adequate C trough after dose intervention | No | 2 | 9 | 5 (3‐7) | <0.001* |
| Yes | 21 | 91 | 55 (8‐264) | ||
*
Statistically significant.
Abbreviations: C trough, plasma trough concentration; PFS, progression‐free survival.