TABLE 1.
Effects of NMDA, glycine or NMDA+glycine on the spontaneous and the depolarization‐evoked transmitter release
| Spontaneous release | Depolarization‐evoked release | |||||
|---|---|---|---|---|---|---|
| NMDA | Glycine | NMDA/glycine | NMDA | Glycine | NMDA/glycine | |
| Dopamine | ↑ | n.e. | ↑ ↑ | n.d. | n.d. | n.d. |
| Noradrenaline | ↑ | n.e. | ↑ ↑ | n.d. | n.d. | n.d. |
| Acetylcholine | n.e. | n.e. | n.e. | ↑ | n.e. | n.d. |
| GABA | n.d. | n.d. | ↑ | n.d. | n.d. | n.d. |
| CCK‐LI/SRIF‐LI | n.e. | n.e. | n.e. | ↑ | ↑ | ↑; n.a. |
| Glutamate | ↑ | n.e. | ↑ ↑ | n.d. | n.d. | n.d. |
Note. ↑/↑↑, increased transmitter release; n.d., not determined; n.e., no effect; n.a., not additive.