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PGE-2 immunoreaction in the groups. (A): Negative immunoreaction in a kidney of a rat belonging control group, (B): Marked PGE2 expression in numerous proximal tubular epithelium (arrows) in a rat from MTX treated group, (C): PGE2 expression in some tubules (arrows) in a kidney from MTX + GA group, Streptavidin biotin peroxidase method, Bars = 100 μm.
