Table 3.
Statistical analysis results of histopathological and immunohistochemical scoring results of kidney.
| Control | MTX | MTX + GA | |||
|---|---|---|---|---|---|
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|
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| Mean ± SD (max-min) | Mean ± SD (max-min) | P values | Mean ± SD (max-min) | P values | |
| Histopathology | 0.00 ± 0.00 (0–0) | 2.40 ± 0.69* (1–3) | 0.001 | 0.50 ± 0.16** (0–1) | 0.001 |
| CRP | 0.00 ± 0.00 (0–0) | 1.90 ± 0.73* (1–3) | 0.001 | 0.00 ± 0.00** (0–0) | 0.001 |
| TNF alpha | 0.00 ± 0.00 (0–0) | 1.60 ± 0.69* (1–2) | 0.001 | 0.40 ± 0.51** (0–1) | 0.001 |
| PGE-2 | 0.00 ± 0.00 (0–0) | 2.20 ± 0.78* (1–3) | 0.001 | 0.80 ± 0.91** (0–2) | 0.001 |
| SAA | 0.00 ± 0.00 (0–0) | 1.90 ± 0.73* (1–3) | 0.001 | 0.00 ± 0.00** (0–0) | 0.001 |
- Values are presented as means ± SD. The relationships between groups and results of histochemical markers area assessed by one-way ANOVA and Bonferroni Dunn tests.
- MTX: Methotrexate, GA: Gallic Acid, CRP: C-Reactive Protein, TNF α: Tumor Necrosis Factor Alpha, PGE-2: Prostaglandin E2.
- p values statistically significant compared with *: Control and **: MTX groups.