. 2016 Nov 5;25(4):872–880. doi: 10.1016/j.jfda.2016.09.002

Table 1.

Effects of yam extracts, including JW, JE, AW, AE, PW, and PE, on cardiac physical and functional parameters in DOX-treated mice.

	Normal	DOX	DOX + yam extracts

			DOX + JW	DOX + JE	DOX + AW	DOX + AE	DOX + PW	DOX + PE
Body weight (g)	30.40 ± 1.71^b	23.98 ± 1.52^a	24.60 ± 1.90^a	23.64 ± 1.72^a	23.28 ± 2.73^a	23.53 ± 2.44^a	23.04 ± 0.98^a	24.49 ± 2.70^a
Heart weight (mg)	168.77 ± 13.99^c	115.60 ± 16.45^a	124.35 ± 20.12^ab	127.16 ± 15.10^ab	127.21 ± 14.32^ab	139.26 ± 9.24^b	123.68 ± 9.73^ab	129.31 ± 17.81^ab
Heart weight/body weight ratio	5.75 ± 0.52^b	4.79 ± 0.87^a	5.05 ± 0.82^ab	5.38 ± 0.64^ab	5.46 ± 0.62^b	5.92 ± 0.39^b	5.37 ± 0.42 ^ab	5.28 ± 0.73^ab
Heart rate (bpm)	616.10 ± 9.25^d	594.18 ± 18.02^a	596.30 ± 17.01^ab	610.60 ± 9.09^cd	601.75 ± 15.99^ab	603.90 ± 9.44^bc	599.50 ± 15.37^ab	603.70 ± 13.77^bc
Blood pressure (mmHg)	115.95 ± 11.59^d	124.09 ± 8.42^e	103.95 ± 9.71^bc	96.40 ± 12.17^a	103.70 ± 9.95^bc	93.35 ± 12.94^a	110.25 ± 11.32^cd	98.75 ± 11.82^a
Serum LDH (U/L)	167.77 ± 24.24^a	292.35 ± 66.96^c	229.69 ± 27.78^ab	191.91 ± 36.72^a	221.93 ± 55.92^ab	169.72 ± 27.71^a	208.29 ± 27.62^ab	204.74 ± 33.14^ab

Values are mean ± SD, n = 10.

^a–e

Means in a row without a common letter differ, p < 0.05.

AE = ethanol extracts of D. alata; AW = water extracts of D. alata (Ta-Shan); bpm = beats per minute; DOX = doxorubicin; JE = ethanol extracts of D. japonica Thunb.; JW = water extracts of D. japonica Thunb.; LDH = lactate dehydrogenase; PE = ethanol extracts of D. purpurea; PW = water extracts of D. purpurea; SD = standard deviation.