Table 3.
Effect of different diet on plasma lipids and glucose in Syrian hamsters for 6 weeks.
| CON | HF | HF + GHE | HF + PO | |
|---|---|---|---|---|
| Triacylglycerol (mg/dL) | 56.4 ± 27.0 | 88.4 ± 9.6** | 70.6 ± 19.9* | 95.5 ± 31.6 |
| Total cholesterol (mg/dL) | 90.6 ± 8.2 | 181.3 ± 19.7** 157.6 ± 23.9* 146.9 ± 10.6* | ||
| HDL-C (mg/dL) | 62.9 ± 5.9 | 103.5 ± 8.0** | 102.4 ± 12.1 | 93.9 ± 14.5 |
| LDL-C (mg/dL) | 15.1 ± 6.7 | 54.8 ± 19.6** | 36.6 ± 12.8* | 25.5 ± 12.3* |
| VLDL-C (mg/dL) | 12.6 ± 4.6 | 23.0 ± 5.7** | 18.6 ± 5.6 | 27.5 ± 6.2 |
| LDL-C +VLDL-C (mg/dL) | 27.7 ± 4.1 | 77.8 ± 17.5** | 55.2 ± 16.0* | 53.0 ± 11.5* |
| TC/HDL-C ratio | 1.4 ± 0.1 | 1.8 ± 0.2** | 1.5 ± 0.1* | 1.6 ± 0.2 |
| AST (U/L) | 12.4 ± 6.1 | 20.2 ± 7.8** | 12.9 ± 3.2* | 11.8 ± 2.1* |
| ALT (U/L) | 15.1 ± 3.0 | 21.1 ± 7.2** | 15.0 ± 3.1* | 14.4 ± 3.7* |
Results are expressed as mean ± SD for eight Syrian hamsters.
*
Significant difference from the HF group at p < 0.05;
**
significant difference from the CON group at p < 0.05.
ALT, alanine aminotransferase; AST, aspartate aminotransferase; CON, control; HDL-C, high-density-lipoprotein cholesterol; HF, high fat; HF + GHE, high fat + Gelidium amansii hot-water extracts; HF + PO, high fat + probucol; LDL-C, low-density lipoprotein cholesterol; TC, total cholesterol; VLDL-C, very-low-density lipoprotein cholesterol.