Table 2. ELISA results and endpoint titers for vaccinee and naturally infected individual serum samples from persons in Colombia*.
Group | Patient ID | Nucleocapsid IgG ELISA† | Neutralizing titer by PRNT50 |
||||||
---|---|---|---|---|---|---|---|---|---|
WT | Mu | Alpha | Beta | Gamma | Delta | Omicron | |||
AstraZeneca |
AZ2 | 0.15 | 204 | 41 | 154 | 79 | 64 | 77 | 13 |
AZ3 | 0.07 | 453 | 123 | 381 | 305 | 306 | 470 | 25 | |
AZ4 | 0.11 | 75 | 3 | 91 | 16 | 20 | 24 | 6 | |
AZ5 | 0.12 | 76 | 9 | 104 | 3 | 13 | 29 | 2 | |
AZ6 | 0.13 | 34 | 4 | 45 | 3 | 23 | 15 | 0 | |
AZ9 | 0.08 | 179 | 35 | 189 | 75 | 128 | 84 | 10 | |
AZ10 |
0.07 |
319 |
9 |
153 |
47 |
55 |
26 |
8 |
|
Pfizer-BioNTech |
PF1 | 0.14 | 119 | 9 | 85 | 1 | 18 | 38 | 3 |
PF2 | 0.04 | 28 | 3 | 43 | 35 | 15 | 17 | 3 | |
PF3 | 0.15 | 262 | 62 | 158 | 130 | 101 | 149 | 19 | |
PF4 | 0.06 | 754 | 121 | 715 | 204 | 226 | 187 | 43 | |
PF5 | 0.05 | 501 | 87 | 320 | 48 | 91 | 259 | 9 | |
PF6 | 0.07 | 123 | 10 | 119 | 52 | 15 | 11 | 3 | |
PF7 | 0.19 | 214 | 9 | 70 | 5 | 0 | 125 | 3 | |
PF8 | 0.05 | 207 | 18 | 167 | 28 | 25 | 66 | 3 | |
PF9 | 0.09 | 715 | 10 | 273 | 0 | 46 | 108 | 2 | |
PF10 |
0.62 |
1043 |
132 |
1036 |
343 |
333 |
799 |
47 |
|
Sinovac |
SVN1 | 2.96 | 51 | 54 | 72 | 36 | 66 | 83 | 0 |
SVN2 | 1.68 | 47 | 9 | 24 | 23 | 21 | 22 | 0 | |
SVN3 | 0.46 | 41 | 6 | 1 | 1 | 18 | 1 | 0 | |
SVN4 | 2.43 | 118 | 61 | 151 | 111 | 89 | 87 | 25 | |
SVN7 | 0.97 | 363 | 162 | 347 | 407 | 188 | 259 | 56 | |
SVN8 | 0.81 | 303 | 5 | 93 | 26 | 30 | 61 | 5 | |
SVN9 | 0.69 | 53 | 0 | 32 | 3 | 15 | 35 | 0 | |
SVN10 | 1.61 | 65 | 4 | 27 | 0 | 10 | 66 | 1 | |
SVN12 | 0.29 | 52 | 8 | 52 | 1 | 20 | 21 | 0 | |
SVN13 | 0.39 | 387 | 24 | 126 | 126 | 35 | 130 | 7 | |
SVN15 | 2.81 | 145 | 175 | 168 | 197 | 147 | 133 | 19 | |
SVN16 | 0.40 | 67 | 2 | 6 | 25 | 10 | 21 | 3 | |
SVN17 | 0.07 | 24 | 1 | 1 | 5 | 0 | 15 | 3 | |
SVN18 | 0.37 | 65 | 0 | 3 | 4 | 0 | 24 | 7 | |
SVN20 |
1.88 |
686 |
464 |
612 |
155 |
131 |
503 |
16 |
|
Naturally infected | EA210 | ND | 696 | 146 | 825 | 595 | 167 | 177 | 2 |
EA234 | ND | 142 | 4 | 86 | 83 | 67 | 9 | 0 | |
EA238 | ND | 1,080 | 48 | 1080 | 314 | 541 | 79 | 5 | |
EA245 | ND | 70 | 2 | 61 | 154 | 44 | 0 | 0 | |
EA332 | ND | 93 | 10 | 43 | 94 | 1 | 20 | 0 | |
EA334 | ND | 140 | 6 | 74 | 115 | 7 | 16 | 3 | |
EA340 | ND | 77 | 2 | 24 | 61 | 0 | 14 | 2 | |
EA352 | ND | 1,080 | 113 | 1,080 | 578 | 870 | 59 | 3 | |
EA354 | ND | 336 | 119 | 423 | 972 | 90 | 628 | 0 | |
EA380 | ND | 918 | 43 | 281 | 630 | 151 | 63 | 17 | |
EA396 | ND | 139 | 24 | 98 | 88 | 14 | 21 | 0 | |
EA413 | ND | 1,080 | 18 | 864 | 1,080 | 260 | 17 | 11 | |
EA422 | ND | 2 | 20 | 28 | 6 | 123 | 100 | 0 | |
EA439 | ND | 398 | 171 | 283 | 812 | 79 | 62 | 9 | |
EA485 | ND | 357 | 87 | 531 | 206 | 114 | 14 | 0 | |
EA501 | ND | 17 | 13 | 86 | 80 | 1 | 0 | 2 | |
EA520 | ND | 166 | 36 | 154 | 211 | 16 | 141 | 1 |
*AstraZeneca (AZD1222), https://www.astrazeneca.com; Pfizer-BioNTech (BNT162b2), https://www.pfizer.com; Sinovac (CoronaVac), http://www.sinovac.com. ND, not determined; PRNT50, 50% plaque reduction neutralization test; WT, wild-type. †Cut-off ≥0.8 was considered positive.