Table 1.

The function of miRNAs in adaptive immunity.

miRNA	Type of immunity	Functions	References
miR-28	Cellular immunity	Silences PD-1 and attenuates the exhaustion of T cells	[32]
miR-155	Cellular immunity	Activates the expression of PD-L1	[33]
miR-195	Cellular immunity	Inhibits CD4T cells through CCDC88C	[34]
miR-448	Cellular immunity	Inhibits IDO1 and enhances CD8+ T cell response	[36]
miR-181a	Cellular immunity	Control TCR signal	[38]
miR-126	Cellular immunity	Acts on IRS-1, regulates T cell activation	[39]
miR-150	Humoral immunity	Acts on BCR, controls B cell differentiation	[40]
miR-34a	Humoral immunity	Affects BCR signaling by the DDR/miR-34a axis	[41]