TABLE 1.
Prediagnosis Characteristics According to the Fluid Dose, Before and After Propensity Score Weighting
| Patient Characteristics | Before PS-Weighting | After PS-Weighting | ||||
|---|---|---|---|---|---|---|
| Fluid 0–29.9 mL/kg (n = 6,074) | Fluid ≥ 30 mL/kg (n = 2,340) | Unweighted SMD, % | Fluid 0–29.9 mL/kg (N* = 6,082) | Fluid ≥ 30 mL/kg (N* = 2,317)* | Weighted SMD, % | |
| Demographic information | ||||||
| Age at diagnosis (yr) | 70 ± 16 | 68 ± 17 | 12.3 | 70 ± 16 | 70 ± 16 | 0.2 |
| Sex (male) | 58.6 | 45.2 | 27.1 | 54.7 | 54.1 | 1.2 |
| Race | ||||||
| American Indian/Alaskan Native | 0.8 | 0.6 | 3.2 | 0.8 | 0.4 | 5.1 |
| Asian | 1.5 | 2.6 | 7.2 | 1.9 | 2.1 | 1.3 |
| Black | 2.7 | 2.7 | 0.1 | 2.7 | 2.8 | 0.3 |
| Native Hawaiian/Pacific Islander | 0.1 | 0.2 | 2.4 | 0.1 | 0.2 | 1.1 |
| White | 92.2 | 90.4 | 6.5 | 91.8 | 91.1 | 2.2 |
| Other/unknown | 2.6 | 3.5 | 5.6 | 2.7 | 3.4 | 4.4 |
| Comorbidities | ||||||
| Chronic obstructive pulmonary disease | 12.7 | 11.2 | 4.9 | 12.3 | 11.9 | 1.1 |
| Hypertension | 44.6 | 37.6 | 14.3 | 42.5 | 41.8 | 1.4 |
| Chronic kidney disease | 22.8 | 16.2 | 16.7 | 20.9 | 20.4 | 1.2 |
| Diabetes | 24.8 | 19.4 | 13.1 | 23.2 | 22.5 | 1.7 |
| Coronary artery disease | 21.2 | 17.3 | 10.0 | 20.1 | 19.5 | 1.5 |
| Congestive heart failure | 18.9 | 10.3 | 24.6 | 16.4 | 15.7 | 2.0 |
| Obesity | 31.9 | 21.0 | 24.9 | 28.8 | 28.1 | 1.4 |
| Dialysis | 3.9 | 3.0 | 4.7 | 3.6 | 3.8 | 0.8 |
| Hospital information | ||||||
| Hospital type (destination) | 60.9 | 65.2 | 8.8 | 62.3 | 63.5 | 2.5 |
| In ICU prior to diagnosis | 16.9 | 20.2 | 8.5 | 17.8 | 17.5 | 0.9 |
| Lactate measurement at diagnosis | 40.9 | 61.9 | 43.0 | 46.9 | 47.5 | 1.3 |
N* = sum of propensity score weights, PS = propensity score, SMD = standardized mean difference.
Numerical characteristics are given as mean ± sd, while categorical characteristics are given as the percentage of patients.