Table 1.
Demographic, clinical, and sampling characteristics of culture-confirmed enteric fever cases included in the longitudinal kinetic analysis, by country
| Bangladesh (n=407) | Nepal (n=543) | Pakistan (n=399) | Ghana (n=71) | Total (n=1420) | ||
|---|---|---|---|---|---|---|
| Age, years | 5·4 (3·2–8·0) | 20·9 (15·7–26·4) | 5·3 (3·0–12·0) | 8·0 (6·0–12·0) | 9·0 (4·5–19·7) | |
| Age strata | ||||||
| <5 years | 179 (44·0%) | 12 (2·2%) | 181 (45·4%) | 11 (15·5%) | 383 (27·0%) | |
| 5–15 years | 227 (55·8%) | 127 (23·4%) | 152 (38·1%) | 52 (73·2%) | 558 (39·3%) | |
| >16 years | 1 (0·2%) | 404 (74·4%) | 66 (16·5%) | 8 (11·3%) | 479 (33·7%) | |
| Missing data | 0 | 0 | 0 | 0 | 0 | |
| Sex | ||||||
| Male | 213 (52·3%) | 302 (55·6%) | 228 (57·1%) | 41 (57·7%) | 784 (55·2%) | |
| Female | 194 (47·7%) | 241 (44·4%) | 171 (42·9%) | 29 (40·8%) | 635 (44·7%) | |
| Missing data | 0 | 0 | 0 | 1 (1·4%) | 1 (0·1%) | |
| Number of serum samples collected per participant | 2·0 (2·0–3·0) | 2·0 (2·0–4·0) | 3·0 (2·0–5·0) | 4·0 (1·5–5·0) | 3·0 (2·0–4·0) | |
| Study enrollment duration, days | 184·0 (28·0–540·5) | 366·0 (160·0–595·5) | 699·0 (367·5–712·0) | 270·0 (14·5–365·0) | 382·0 (94·0–696·0) | |
| Reported number of days of fever at presentation | 4·0 (3·0–6·0) | 4·0 (3·0–6·0) | 6·0 (4·0–9·0) | 6·0 (3·0–7·0) | 4·0 (3·0–7·0) | |
| Hospitalised | ||||||
| No | 326 (80·1%) | 372 (68·5%) | 210 (52·6%) | 31 (43·7%) | 939 (66·1%) | |
| Yes | 81 (19·9%) | 156 (28·7%) | 188 (47·1%) | 33 (46·5%) | 458 (32·3%) | |
| Missing data | 0 | 15 (2·8%) | 1 (0·3%) | 7 (9·9%) | 23 (1·6%) | |
| Salmonella enterica serovar | ||||||
| S Paratyphi A | 56 (13·8%) | 86 (15·8%) | 11 (2·8%) | 0 | 153 (10·8%) | |
| S Typhi | 351 (86·2%) | 457 (84·2%) | 388 (97·2%) | 71 (100%) | 1267 (89·2%) | |
| Missing data | 0 | 0 | 0 | 0 | 0 | |
| Vaccine status | ||||||
| Typhoid conjugate vaccine | 1 (0·2%) | 1 (0·2%) | 4 (1·0%) | 0 | 6 (0·4%) | |
| Other typhoid vaccine | 1 (0·2%) | 1 (0·2%) | 8 (2·0%) | 0 | 10 (0·7%) | |
| Not vaccinated | 405 (99·5%) | 541 (99·6%) | 378 (94·7%) | 71 (100%) | 1395 (98·2%) | |
| Missing data | 0 | 0 | 9 (2·3%) | 0 | 9 (0·6%) | |
Data are median (IQR) or n (%)