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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: Nat Med. 2022 May 26;28(7):1398–1405. doi: 10.1038/s41591-022-01822-2

Extended Data Fig. 1. Plasma P-tau181 and P-tau217 levels by clinical diagnosis and amyloid PET status.

Extended Data Fig. 1

Abnormal amyloid PET (A+) was defined as standard uptake value ratio (SUVR)>1.48 using PiB-PET. P-values are from two-sided Wilcoxon rank-sum tests without adjustment for multiple comparisons. Box plots display the median, 25th percentile, 75th percentile (middle, bottom, and top bars of the box), and the whiskers go out to 1.5 times the interquartile range (75th percentile – 25th percentile) from the 25th and 75th percentile. CU, cognitively unimpaired; MCI, mild cognitive impairment; DEM, dementia.