Table 1:
Descriptive Statistics
| Variable | Unit | Alive without re-transplant after 1 years (n=16,964) | Death or re-transplant within 1 years (n=2,936) | p-value | |||
|---|---|---|---|---|---|---|---|
| N | % | N | % | Raw | Bonferroni | ||
| Gender | Female | 7,019 | 41% | 1,090 | 37% | <0.001 | <0.001 |
| Mechanical Ventilation | Yes | 930 | 5% | 314 | 11% | <0.001 | <0.001 |
| Number of Lungs | Both Lungs | 11,604 | 68% | 1,884 | 64% | <0.001 | 1.9e-<0.001 |
| Multi-Organ Transplant | More than one | 50 | <1% | 15 | <1% | 0.085 | >0.99 |
| Medical Condition | ICU | 1,171 | 9% | 831 | 13% | <0.001 | <0.001 |
| Hospitalized | 1,148 | 8% | 595 | 9% | |||
| Not Hospitalized | 11,293 | 83% | 4,862 | 77% | |||
| Diabetes | None | 11,027 | 81% | 4,972 | 79% | 0.3 | >0.99 |
| Type I | 431 | 3% | 240 | 4% | |||
| Type II | 1,551 | 11% | 789 | 13% | |||
| Other | 531 | 4% | 242 | 4% | |||
| Unknown | 72 | 1% | 45 | 1% | |||
| Dialysis prior to LTx | Yes | 52 | <1% | 46 | 1% | <0.001 | <0.001 |
| No | 9,399 | 69% | 4,621 | 73% | |||
| Unknown | 4,161 | 31% | 1,621 | 26% | |||
| Cigarette Use | Yes | 8,053 | 59% | 3,722 | 59% | 0.86 | >0.99 |
| No | 5,252 | 39% | 2,400 | 38% | |||
| Unknown | 307 | 2% | 166 | 3% | |||
| Steroid | Yes | 6,117 | 45% | 3,051 | 49% | <0.001 | <0.001 |
| No | 7,212 | 53% | 3,104 | 49% | |||
| Unknown | 283 | 2% | 133 | 2% | |||
| CMV Status | Positive | 7,415 | 54% | 3,437 | 55% | 0.23 | >0.99 |
| Negative | 5,673 | 42% | 2,603 | 41% | |||
| Unknown | 524 | 4% | 248 | 4% | |||
| Functional Status | No assistance | 632 | 5% | 244 | 4% | <0.001 | <0.001 |
| Some assistance | 9,282 | 68% | 3,936 | 63% | |||
| Total Assistance | 744 | 5% | 443 | 7% | |||
| Unknown | 2,954 | 22% | 1,665 | 26% | |||
| Race | White | 11,316 | 83% | 5,239 | 83% | 0.86 | >0.99 |
| Black | 1,184 | 9% | 552 | 9% | |||
| Asian | 212 | 2% | 90 | 1% | |||
| Pacific Islander | 10 | <1% | 7 | 1% | |||
| American Indian | 46 | <1% | 16 | <1% | |||
| Hispanic | 804 | 6% | 370 | 6% | |||
| Multi-Racial | 46 | <1% | 17 | <1% | |||
| Insurance | Private | 7,250 | 53% | 3,198 | 51% | 0.12 | >0.99 |
| Medicaid | 873 | 6% | 449 | 7% | |||
| Medicare | 4,970 | 37% | 2,448 | 39% | |||
| Other | 447 | 3% | 165 | 2% | |||
| None | 72 | <1% | 28 | <1% | |||
| Education | No High School | 337 | 2% | 161 | 3% | 0.2 | >0.99 |
| High School or GED | 4,936 | 36% | 2,349 | 37% | |||
| Attended College | 3,446 | 25% | 1,575 | 25% | |||
| Associate/Bachelor | 2,742 | 20% | 1,111 | 18% | |||
| Post-College Graduate | 1,217 | 9% | 589 | 9% | |||
| Unknown | 918 | 7% | 492 | 8% | |||
| Disease | CF | 1,697 | 12% | 702 | 11% | <0.001 | <0.001 |
| COPD | 4,028 | 30% | 1,723 | 27% | |||
| IPF | 5,201 | 38% | 2,588 | 41% | |||
| Other | 2,686 | 20% | 1,275 | 20% | |||
| BMI | Very Low (<17) | 317 | 2% | 206 | 3% | <0.001 | 0.016 |
| Low (17–18.5) | 733 | 5% | 378 | 6% | |||
| Normal (18.5–25) | 5,359 | 39% | 2,252 | 36% | |||
| Overweight (25–30) | 5,055 | 37% | 2,366 | 38% | |||
| Obese (>30) | 2,128 | 16% | 1,076 | 17% | |||
| Unknown | 20 | <1% | 10 | <1% | |||
| N | Mean (SD) | N | Mean (SD) | ||||
| Age | Years | 16,964 | 55.1 (13.1) | 2,936 | 56.5 (13.1) | <0.001 | <0.001 |
| Lung Allocation Score | 16,102 | 41.5 (14.6) | 2,727 | 43.7 (16.5) | <0.001 | <0.001 | |
| FEV1 percent predicted | 16,687 | 38.4 (20.9) | 2,853 | 39.7 (20.2) | 0.002 | 0.052 | |
| FVC percent predicted | 16,748 | 48.6 (17.5) | 2,865 | 47.96 (18.0) | 0.093 | >0.99 | |
| Six Minute Walk | 16,238 | 812.5 (407.0) | 2,764 | 764.1 (425.0) | <0.001 | <0.001 | |
| Pulmonary Arterial Pressure | 15,577 | 27.6 (10.2) | 2,652 | 28.5 (11.2) | <0.001 | 0.004 | |
| PCO2 | 15,064 | 47.9 (13.6) | 2,534 | 47.2 (14.1) | 0.017 | 0.49 | |
| Serum Alb | 11.542 | 3.9 (0.6) | 2,118 | 3.8 (0.7) | <0.001 | <0.001 | |
| Total Bilirubin | 16,764 | 0.61 (0.91) | 2,892 | 0.78 (1.70) | <0.001 | <0.001 | |
| Serum Creatinine | 16,934 | 0.85 (0.43) | 2,928 | 0.90 (0.43) | <0.001 | <0.001 | |
| Time on Waiting List | Days | 16,964 | 196.1 (368.0) | 2,936 | 205.3 (409.0) | 0.25 | >0.99 |
| Oxygen Requirement | 16,521 | 5.1 (4.8) | 2,841 | 5.8 (5.5) | <0.001 | <0.001 | |
| GFR | 16,964 | 93.4 (23.2) | 2,936 | 89.6 (26.0) | <0.001 | <0.001 | |
Differences between binary variables was tested using a test of proportions. For categorical variables, the difference in distributions was tested using a chi-square test. For continuous variables, the difference in means was tested by a t-test. We report both the p-value for each test individually (Raw), and the Bonferroni adjusted p-value (Bonferroni).