Table 2:
Coefficients from the Clinician Model
| Unit | Odds Ratio (95% CI) | Raw P-value | Bonferroni P-value | |
|---|---|---|---|---|
| Female | 0.77 (0.70, 0.85) | <0.01 | <0.01 | |
| Education | High School (Baseline) | |||
| None | 1.25 (0.42, 3.76) | 0.73 | 1.00 | |
| Grade School | 0.93 (0.70, 1.25) | 0.64 | 1.00 | |
| Some College | 0.90 (0.80, 1.01) | 0.08 | 1.00 | |
| College Graduate | 0.91 (0.80, 1.03) | 0.14 | 1.00 | |
| Post Graduate | 1.02 (0.87, 1.20) | 0.81 | 1.00 | |
| Unknown | 1.02 (0.86, 1.21) | 0.82 | 1.00 | |
| Insurance | Private (Baseline) | |||
| None | 0.70 (0.36, 1.37) | 0.30 | 1.00 | |
| Medicare | 1.11 (1.01, 1.23) | 0.03 | 1.00 | |
| Medicaid | 0.88 (0.72, 1.07) | 0.19 | 1.00 | |
| Other | 0.79 (0.60, 1.05) | 0.10 | 1.00 | |
| BMI | Normal (18.5–25) (Baseline) | |||
| Low (<18.5) | 1.45 (1.22, 1.73) | <0.01 | <0.01 | |
| High (>25 – 30) | 1.09 (0.98, 1.22) | 0.11 | 1.00 | |
| Obese (>30) | 1.02 (0.89, 1.17) | 0.74 | 1.00 | |
| Diagnosis | COPD (Baseline) | |||
| CF | 0.70 (0.56, 0.87) | <0.01 | 0.08 | |
| IPF | 1.03 (0.87, 1.22) | 0.73 | 1.00 | |
| Other | 1.08 (0.91, 1.27) | 0.37 | 1.00 | |
| Functional Status | No Assistance (Baseline) | |||
| Some Assistance | 1.18 (0.93, 1.51) | 0.18 | 1.00 | |
| Total Assistance | 0.99 (0.72, 1.35) | 0.95 | 1.00 | |
| Unknown | 1.58 (1.22, 2.05 | <0.01 | 0.02 | |
| Medical Condition | Not Hospitalized (Baseline) | |||
| Hospitalized | 1.32 (1.13, 1.54) | <0.01 | 0.03 | |
| ICU | 2.00 (1.67, 2.38) | <0.01 | <0.01 | |
| Dialysis Prior to LTx | No (Baseline) | |||
| Yes | 2.12 (1.29, 3.48) | <0.01 | 0.15 | |
| Unknown | 0.85 (0.76, 0.94) | <0.01 | 0.13 | |
| Steroids | No (Baseline) | |||
| Yes | 1.06 (0.97, 1.16) | 0.22 | 1.00 | |
| Unknown | 1.03 (0.77, 1.37) | 0.86 | 1.00 | |
| Cigarette Use | No (Baseline) | |||
| Yes | 0.91 (0.82, 1.01) | 0.09 | 1.00 | |
| Unknown | 1.05 (0.75, 1.45) | 0.79 | 1.00 | |
| CMV | Negative (Baseline) | |||
| Positive | 1.00 (0.91, 1.09) | 0.94 | 1.00 | |
| Unknown | 1.07 (0.85, 1.33) | 0.58 | 1.00 | |
| Ventilator Use | 1.38 (1.14, 1.68) | <0.01 | 0.05 | |
| Wait List Time | 100 days | 1.02 (1.00, 1.03) | 0.02 | 0.12 |
| Multi Organ Transplant | 1.49 (0.72, 3.08) | 0.29 | 1.00 | |
| O2 Used | 1L | 1.00 (0.99, 1.01) | 0.73 | 1.00 |
| FEV1 Percent Predicted | 5% | 1.00(0.98, 1.02) | 0.76 | 1.00 |
| FVC Percent Predicted | 5% | 0.99 (0.97, 1.00) | 0.13 | 1.00 |
| Six Minute Walk | 100ft | 0.98 (0.97, 1.00) | 0.01 | 0.41 |
| GFR | 5 mL/min | 0.97 (0.96, 0.98) | <0.01 | 0.01 |
| LAS | 1 unit | 1.00 (0.99, 1.00) | 0.33 | 1.00 |
| Mean Pulmonary Arterial Pressure | 1 mmHg | 1.01 (1.00, 1.01) | 0.02 | 1.00 |
| Serum Albumin | 1 g/dL | 0.81 (0.75, 0.88) | <0.01 | <0.01 |
| Total Bilirubin | 1 g/dL | 1.08 (1.04, 1.11) | <0.01 | <0.01 |
| Serum Creatinine | 1 mg/dL | 1.02 (0.85, 1.21) | 0.86 | 1.00 |
| PCO2 | 1 mmHg | 1.00 (0.99, 1.00) | 0.01 | 0.64 |
The risk score from the clinician model can be calculated by taking the natural log of the odds ratios and summing over each row to get a composite score for each patient.