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. 2022 Jul 27;13:4319. doi: 10.1038/s41467-022-31757-8

Fig. 4. PheWAS of INHBE pLOF.

Fig. 4

The association of INHBE pLOF with quantitative traits (QTs), circulating proteins (Proteins), disease diagnoses (Diagnoses), biomarkers from primary care (GP) and measures of body composition (DEXA) was tested using either a generalized linear regression or a mixed-effects model. The y-axis shows −log10(P) for each trait tested. Phenome-wide significant (P ≤ 1.84 × 10−5 Bonferroni correcting for the number of phenotypes tested; grey line) and suggestive (P ≤ 1 × 10−3; red line) associations are labeled. TGs; triglycerides, Reticulocytes; high light scatter reticulocyte count and percentage, INHBC; inhibin βC/activin C, LRIG1; leucine-rich repeats and immunoglobulin-like domains protein 1.