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. 2022 Jul 27;12:12798. doi: 10.1038/s41598-022-16499-3

Table 3.

DCS variables during the studies among N = 49 days by IVH status.

Variables Total (N = 49 days) No IVH (N = 27) IVH grade I or II (N = 9) IVH grade III or IV (N = 13) P val*
Duration of the measurement (h/day) 4.3 (3.4–5.8) 3.7 (3.0–5.8) 5.0 (4.1–5.8) 5.0 (3.6–6.2) 0.27a
Total data length after MA rejection (h/day) 3.9 ± 1.4 3.6 ± 1.5 4.2 ± 1.2 4.3 ± 1.4 0.33
Motion artifact (%/day) 9.6 (4.9–15.2) 7.4 (4.5–19.8) 11.8 (9.6–20.4) 7.8 (2.9–12.7) 0.28a
SBFid (daily median, e-8 * cm2/s/day) 5.1 (3.1–6.7) 5.1 (3.2–6.2) 7.0 (4.3–9.4) 3.7 (2.7–5.4) 0.04
CBFi (daily median, e-8 * cm2/s/day) 3.2 (2.7–4.4) 3.6 (2.8–4.7) 3.0 (2.8–4.1) 2.7 (2.1–3.4) 0.41a
CVSBFi (SBFi coefficient of variation) (5-min sliding window median, /day) 0.107 (0.09–0.13) 0.124 (0.10–0.15) 0.107 (0.09–0.12) 0.096 (0.08–0.12) 0.76b
CVCBFi (5-min sliding window median, /day) 0.069 ± 0.018 0.070 ± 0.019 0.069 ± 0.020 0.067 ± 0.015 0.95
CVCBFi_20 (20-min sliding window median, /day) 0.089 ± 0.022 0.090 ± 0.025 0.088 ± 0.021 0.085 ± 0.015 0.95
CVCBFi_40 (40-min sliding window median, /day) 0.101 ± 0.027 0.105 ± 0.032 0.100 ± 0.021 0.094 ± 0.016 0.77
RiSC (3-min sliding window mean, /day) 0.56 ± 0.14 0.53 ± 0.14 0.49 ± 0.12 0.65 ± 0.12 0.17
TRiSC (s/day) 2.8 (1.5–4.5) 3.1 (1.5–4.8) 3.7 (2.8–4.4) 2.5 (1.5–3.3) 0.33c
Pressure passiveness indices
Available 17 (35%) 11 (41%) 2 (22%)e 4 (31%) 0.66
MAP × CBF cross-correlation (3-min sliding window mean, /day) 0.35 ± 0.17 0.30 ± 0.11 0.22 ± 0.11 0.55 ± 0.16 0.14
Delay of MAP × CBF correlation (mean, seconds/day) 6.6 ± 3.4 7.7 ± 3.3 7.4 ± 2.4 3.3 ± 1.7 0.29

Significant values are in bold.

MA Motion artifact; *P values were obtained using a linear mixed model (when possible) to account for repeated measures in each subject. The P-values for categorical variables were obtained using Fisher’s exact test without accounting for repeated measures in each subject.; alog10() transformation was applied; blogit() transformation was applied; cSquare root transformation was applied; dThe variable passed the normality test but is presented in median (25–75th) for easy comparison with CBFi; eThe two measurements were from one subject; Data are presented as n (column %) for categorical variables, except when presented as a mean ± SD for normally distributed variables or when presented as a median (25–75th) for non-normal variables.