FIGURE 2.

The combination of our encoders with FFT unveils frequency profiles associated to specific protein folding and functions. We used the encoder of secondary structure combined with FFT to create profiles related to folding and protein functions. (A) Fourier spectra for two family enzymes (hydrolases and ligases) in a dataset of enzyme families. (B,C) Fourier spectra of the same family separated by folding, showing that our methodology is sensitive to apparent differences between alpha and beta folding types. (D) Fourier spectra for alpha and beta folding in a dataset of different protein families. (E,F) Fourier spectra of the same folding separated by protein family, showing that our methodology is sensitive to proteins with the same folding but belonging to different families. N for frequency normalization = 1,024.