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Multivariate Cox analysis of clinical features associated with survival outcomes in the genetically altered subgroup. (A, B) Forest plots showing the mutant subgroup and all relevant clinical features in association with (A) PFS and (B) OS following dCRT treatment by multivariate analysis. Mutant subgroup: patients with any of the MET, NOTCH2 and PTEN loss of function, as well as FGFR and KEAP1-NRF2 pathway gene alterations; ADC: adenocarcinoma; SCC: squamous cell carcinoma.
