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. 2022 Jul 14;10:930355. doi: 10.3389/fcell.2022.930355

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Copyright © 2022 Langlois-Lemay and D’Amours.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cellular changes associated with the quiescent state in yeast. These changes include the disappearance of cytoplasmic microtubules (MTs) and formation of a nuclear bundle of MTs (nMTs) that spans the entire nucleus. Centromeres (shown in yellow) normally cluster together at the end of nuclear MTs in interphase cells (left) but get redistributed along the length of the newly formed nMT bundle in quiescent cells (right). Chromosome arms are omitted from this figure to simplify the representation. See text for more details.