Figure 2.
Data of homologous 3D-structure modeling for putatively mutant ERG11 gene products in Candida spp. assisted by 5JLC as template (http://www.pdb.org). Presumably altered 3D steric conformations of ERG11 enzymes from azole-resistant C. albicans (A), C tropicalis (B), and C. parapsilosis (C) are shown. Red spots indicate mutation sites at the amino-acid level in each Candida spp. resistant against azoles when compared with corresponding reference sequences in GenBank.
Abbreviations: CAL, C. albicans; CTR, C. tropicalis; CPA, C. parapsilosis.