Table 3.
Comparison of clinical variables of invasive Candida infections vs controls
| Patients with invasive Candida infections, n=75 (%) | Patients without Candida, n=60 (%) | P | |
|---|---|---|---|
| Sex | |||
| Male | 33 (44) | 27 (45) | 0.908 |
| Female | 42 (56) | 33 (55) | |
| Age | |||
| Mean ± SD (years) | 57.83±19.26 | 50.60±15.56 | 0.006 |
| 0 – 14 | 3 (4) | 0 | 0.117 |
| 15 – 49 | 21 (28) | 31 (51.67) | 0.005 |
| 50 – 65 | 21 (28) | 19 (31.67) | 0.643 |
| >65 | 30 (40) | 10 (16.67) | 0.003 |
| Hospital staya | |||
| Mean ± SD (days) | 44.44±45.46 | 16.95±13.17 | <0.001 |
| 0 – 7 | 4 (5.33) | 12 (20) | 0.009 |
| 7 – 14 | 22 (29.33) | 23 (38.33) | 0.270 |
| >14 | 49 (65.33) | 25 (41.67) | 0.006 |
| Clinical risk factors | |||
| Invasive interventions | |||
| Surgical procedures | 37 (49.33) | 12 (20) | <0.0001 |
| Urethral catheters | 34 (45.33) | 17 (28.33) | 0.043 |
| Ventilatory support | 24 (32) | 13 (21.67) | 0.181 |
| Tracheal intubation | 23 (30.67) | 14 (23.33) | 0.343 |
| Arteriovenous cannulation | 21 (28) | 17 (28.33) | 0.966 |
| Tracheotomy | 12 (16) | 0 | 0.001 |
| PD or hemodialysis | 3 (4) | 5 (8.33) | 0.289 |
| Immune state | |||
| Immunosuppressive therapy | 3 (4) | 3 (5) | 0.289 |
| Comorbidities | |||
| Cancers | 18 (24) | 5 (8.33) | 0.016 |
| Diabetes mellitus | 7 (9.33) | 7 (11.67) | 0.659 |
| Liver cirrhosis | 1 (1.33) | 0 | 0.369 |
| Concurrent Candida infections | 24 (32) | 0 | <0.0001 |
| Coinfections of bacteria | 49 (65.33) | 28 (46.67) | 0.029 |
| Clinical outcomes | |||
| Improvement | 44 (58.67) | 54 (90) | <0.0001 |
| Deterioration | 8 (10.67) | 6 (10) | 0.900 |
| Moribund | 2 (2.67) | 0 | 0.203 |
Notes: aTotal length of stay for patients with invasive Candida infection or Candida colonization.
Abbreviation: PD, peritoneal dialysis.