Table 5.
Comparison of clinical variables of invasive Candida infection vs colonization
| Patients with Invasive Candida Infections, n=75 (%) | Patients with Candida Colonization, n=58 (%) | P | |
|---|---|---|---|
| Sex | |||
| Male | 33 (44) | 41 (70.69) | 0.002 |
| Female | 42 (56) | 17 (29.31) | |
| Age | |||
| Mean ± SD (years) | 57.83±19.26 | 66.12±14.17 | 0.007 |
| 0 – 14 | 3 (4) | 0 | 0.123 |
| 15 – 49 | 21 (28) | 5 (8.62) | 0.005 |
| 50 – 65 | 21 (28) | 18 (31.03) | 0.703 |
| >65 | 30 (40) | 35 (60.34) | 0.020 |
| Hospital staya | |||
| Mean ± SD (days) | 44.44±45.46 | 29.55±32.90 | 0.037 |
| 0 – 7 | 4 (5.33) | 1 (1.72) | 0.278 |
| 7 – 14 | 22 (29.33) | 14 (24.14) | 0.504 |
| >14 | 49 (65.33) | 43 (74.14) | 0.276 |
| Clinical risk factors | |||
| Invasive interventions | |||
| Surgical procedures | 37 (49.33) | 26 (44.83) | 0.606 |
| Urethral catheters | 34 (45.33) | 32 (55.17) | 0.260 |
| Ventilatory support | 24 (32) | 22 (37.93) | 0.476 |
| Tracheal intubation | 23 (30.67) | 29 (50) | 0.023 |
| Arteriovenous cannulation | 21 (28) | 30 (51.72) | 0.005 |
| Tracheotomy | 12 (16) | 8 (13.79) | 0.724 |
| PD or hemodialysis | 3 (4) | 4 (6.90) | 0.458 |
| Immune state | |||
| Immunosuppressive therapy | 3 (4) | 3 (5.17) | 0.747 |
| Comorbidities | |||
| Cancers | 18 (24) | 27 (46.55) | 0.006 |
| Diabetes mellitus | 7 (9.33) | 9 (15.52) | 0.277 |
| Liver cirrhosis | 1 (1.33) | 2 (3.45) | 0.415 |
| Concurrent Candida infections | 24 (32) | 9 (15.52) | 0.029 |
| Coinfections of bacteria | 49 (65.33) | 42 (72.41) | 0.384 |
| Clinical outcomes | |||
| Improvement | 44 (58.67) | 40 (68.97) | 0.222 |
| Deterioration | 8 (10.67) | 2 (3.45) | 0.117 |
| Moribund | 2 (2.67) | 1 (1.72) | 0.717 |
Notes: aTotal length of stay for patients with invasive Candida infection or Candida colonization.
Abbreviation: PD, peritoneal dialysis.