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. 2022 Jul 22;10(8):1776. doi: 10.3390/biomedicines10081776

Figure 1.

Figure 1

6-OHDA induced selective degeneration of SNc dopamine neurons. (A) Diagram showing the two targeted 6-OHDA injection sites in the striatum, where it is taken up by SNc axonal terminals. (B) Immunohistochemistry for TH in the SNc and neighboring VTA of mice that received unilateral injections of 6-OHDA (top). Immunohistochemistry for TH overlaid with NeuN shows the selectivity of 6-OHDA for dopamine neurons (bottom), n = 3 mice.