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. 2022 Jul 22;14(8):1527. doi: 10.3390/pharmaceutics14081527

Figure 3.

Figure 3

Effects of AIT delivered with hydrogel in comparison to standard AIT treatment on BALF cells and cytokines. (a) Schematic overview of AIT in a murine model of allergic asthma. (b) Total BALF cell count (n = 10). (c) Differential cell counts of eosinophils, neutrophils, natural killer cells, and CD4+ cells in the BALF (n = 10). (d) Levels of IL-4, IL-13, IFN-γ, IL-10, and IL-17A analyzed in the BALF (n = 10). Gaussian and non-Gaussian distributed results were analyzed by unpaired t-test or Mann–Whitney test, respectively. p-values of ≤0.05, ≤0.01, ≤0.001, and ≤0.0001 are shown as *, **, ***, and ****, respectively. p-values of AIT groups compared to the respective non-allergic groups are shown as +, ++, +++, and ++++, respectively.