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. 2022 Jul 14;13:914812. doi: 10.3389/fendo.2022.914812

Table 4.

Subgroup analysis between METS-IR index with kidney stone formation.

Characteristic Model 1 OR (95%CI) Model 2 OR (95%CI) Model 3 OR (95%CI) p for trend* p for interaction*
Stratified by gender 0.4694
 Male 1.0179 (1.0140, 1.0218) 1.0185 (1.0144, 1.0227) 1.0123 (1.0078, 1.0168) <0.001
 Female 1.0191 (1.0152, 1.0230) 1.0201 (1.0161, 1.0241) 1.0117 (1.0072, 1.0161) <0.001
Stratified by age (years) 0.7463
 20-39 1.0157 (1.0101, 1.0214) 1.0158 (1.0101, 1.0215) 1.0068 (1.0004, 1.0132) 0.025
 40-59 1.0202 (1.0156, 1.0248) 1.0207 (1.0160, 1.0254) 1.0128 (1.0076, 1.0180) <0.001
 60-80 1.0195 (1.0148, 1.0243) 1.0187 (1.0138, 1.0117 (1.0064, 1.0171) <0.001
Stratified by hypertension 0.0651
 NO 1.0189 (1.0149, 1.0230) 1.0193 (1.0150, 1.0236) 1.0152 (1.0107, 1.0197) <0.001
 YES 1.0102 (1.0063, 1.0142) 1.0122 (1.0080, 1.0164) 1.0074 (1.0029, 1.0118) 0.001
Stratified by diabetes 0.3559
 NO 1.0163 (1.0130, 1.0195) 1.0172 (1.0138, 1.0207) 1.0134 (1.0098, 1.0170) <0.001
 YES 1.0094 (1.0036, 1.0152) 1.0108 (1.0045, 1.0170) 0.000670 1.0075 (1.0011, 1.0140) <0.001

Model 1 = no covariates were adjusted.

Model 2 = Model 1+age,gender,race were adjusted.

Model 3 = adjusted for all covariates except effect modifier.

*Means only in model 3.