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. 2022 Jul 14;13:935257. doi: 10.3389/fgene.2022.935257

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Copyright © 2022 Sampson, Wolska, Meeusen, Donato, Jaffe and Remaley.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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VLDL-C by calculation versus β-quantification. VLDL-C was calculated from the results of a standard lipid panel in the validation dataset (N = 12,405) by the Friedewald VLDL-C formula (F-VLDL-C) (A), the Sampson VLDL-C equation (S-VLDL-C) (B), and the enhanced Sampson VLDL-C equation (eS-VLDL-C) (C) and plotted against VLDL-C as measured by BQ. Solid lines are the linear fit for indicated regression equations. Dashed lines are the line of identity. Results are color-coded by TG levels with the value in the legend indicating the start of each interval.