FIGURE 1.

Binding surfaces identification and separation into connected components for Human Hedgehog acyltransferase in complex with two Fab antibody fragments (pdb code: 7MHY). In cyan the surface of the antibody fragment; in white, the antigen. The paratope, shown in the left bottom, is in gray while the different connected components of the epitope surface are colored in green and red, respectively. On the right: zoom of the epitope surface patches. Each color indicates a distinct connected component of the epitope. Components that are a fraction below 5% of the total contact area are discarded, yielding in this case two residual components.