TABLE 1.
Demographic and clinical variables of included studies
| Authors & Year | Study Design | No. of Pts | Age, Sex | Pathology | Pts w/ Pain | Pts w/ Neurological Deficit | Level of Manifestation | Main Microorganism | Surgery | Antimicrobial Treatment Duration | FU |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Arockiaraj et val., 20188 |
CS |
6 |
Mean 12 yrs, 2 M, 1 F |
Tuberculosis spondylodiscitis (3) |
3 |
2 |
Thoracic (3), multifocal (1) |
Mycobacterium tuberculosis (3) |
Pst decompression (2), costotransversectomy (1) |
NA |
Mean 12 mos |
| Banerjee et al., 20119 |
CR |
1 |
4 wks, M |
C1–2 vertebral osteomyelitis |
NA |
1 |
Cervical (1) |
Staphylococcus aureus
|
Surgical drainage of RPA |
NA |
NA |
| Glotzbecker et al., 201510 |
CR |
1 |
3 mos, M |
C1–2 vertebral osteomyelitis |
NA |
1 |
Cervical (1) |
Staphylococcus aureus
|
Occiput - C2 pst instrumented fusion |
NA |
50 mos |
| Imakiire et al., 202011 |
CR |
1 |
3 yrs, F |
Bacillus Calmette-Guérin–associated cervical spondylitis |
0 |
0 |
Cervical (1) |
Mycobacterium bovis |
Extracorporeal fusion; bone transplant, on collapsed C4 vertebrae |
9 mos |
12 mos |
| Ishihama et al., 202012 |
CR |
1 |
9 yrs, F |
L5–S1 spondylodiscitis |
1 |
1 |
Lumbar (1) |
Staphylococcus aureus
|
Transforaminal discectomy |
NA |
12 mos |
| Karim et al., 202213 |
CR |
1 |
15 yr, M |
L5–S1 discitis |
1 |
0 |
Lumbar (1) |
Klebsiella aerogenes |
Abscess drainage |
6 mos |
9 mos |
| Papp et al., 201314 |
CR |
1 |
4 wks, M |
C1–2 vertebral osteomyelitis, T5–7 epidural abscess |
NA |
1 |
Cervical (1) |
Staphylococcus aureus
|
Hemisemilaminectomy; RPA & epidural abscess drainage |
6 wks |
36 mos |
| Park et al., 201715 |
CR |
1 |
6 mos, NA |
C2 odontoid osteomyelitis |
1 |
0 |
Cervical (1) |
Staphylococcus aureus
|
Surgical drainage of RPA |
3 mos |
18 mos |
| Pinto et al., 202116 |
CS |
41 |
Mean 9 yrs, 11 M, 15 F |
Tuberculosis spondylodiscitis (26) |
NA |
26 |
Cervical (2), thoracic (22), lumbar (7), multifocal (4) |
Mycobacterium tuberculosis (26) |
Pst decompression alone (6); decompression, pst instrumented fusion (8); decompression, pst instrumented fusion, ant reconstruction (12) |
NA |
Mean 31 mos |
| Romano et al., 202117 |
CR |
1 |
4 wks, M |
T12–L1 spondylodiscitis |
NA |
0 |
Thoracolumbar (1) |
Staphylococcus aureus
|
Decompression, pst instrumented T11–L2 fusion, ant reconstruction |
NA |
9 yrs |
| Tsirikos & Tome-Bermejo, 201218 |
CR |
1 |
8 wks, M |
T4–5 spondylodiscitis |
1 |
0 |
Thoracic (1) |
Staphylococcus aureus
|
T2–7 pst spinal fusion, T3–6 ant spinal fusion |
11 mos |
4 yrs |
| Vibert et al., 201819 | CR | 1 | 13 yrs, M | T11–L1 vertebral osteomyelitis | 1 | 1 | Thoracolumbar (1) | Staphylococcus aureus | T12–L2 kyphectomy, T7–S1 pst instrumentation | 3 mos | 18 mos |
CR = case report; CS = case series; FU = follow-up; NA = not applicable; pst = posterior; Pts = patients; Tx = treatment.