Table 2. Relationship between the presence of blaVEB, blaGES, and blaPER genes in clinical isolates of P. aeruginosa and resistance to beta-lactams.
| Genes |
Number (%) of isolates containing β-lactamase encoding genes |
||||||
|
blaVEB
|
blaGES
|
blaPER
|
|||||
| Antibiotics and antibiotic resistance pattern (number) | positive | negative | positive | negative | positive | negative | |
| Piperacillin | R (26) | 24 (92.3) | 2 (7.69) | 23 (88.46) | 3 (11.53) | 25 (96.15) | 1 (3.84) |
| I (21) | 12 (57.14) | 9 (42.85) | 11 (52.38) | 10 (47.61) | 9 (42.85) | 12 (57.14) | |
| S (53) | 4 (7.54) | 49 (92.45) | 2 (3.77) | 51 (96.22) | 1 (1.18) | 52 (98.11) | |
|
| |||||||
| Piperacillin-tazobactam | R (12) | 11 (91.66) | 1 (8.33) | 11 (91.66) | 1 (8.33) | 11 (91.66) | 1 (8.33) |
| I (11) | 10 (90.9) | 1 (9.09) | 9 (81.81) | 2 (18.18) | 9 (81.81) | 2 (18.18) | |
| S (77) | 19 (24.67) | 58 (75.32) | 16 (20.77) | 61 (79.22) | 15 (19.48) | 62 (80.51) | |
|
| |||||||
| Aztreonam | R (39) | 36 (92.3) | 3 (7.69) | 33 (84.61) | 6 (15.38) | 32 (82.05) | 7 (17.94) |
| I (33) | 4 (12.12) | 29 (87.87) | 3 (9.09) | 30 (90.9) | 3 (9.09) | 30 (90.9) | |
| S (28) | - | 28 (100) | - | 28 (100) | - | 28 (100) | |
|
| |||||||
| Ceftazidime | R (27) | 26 (96.29) | 1 (3.7) | 24 (88.88) | 3 (11.11) | 26 (96.29) | 1 (3.7) |
| I (2) | 2 (100) | - | 2 (100) | - | 1 (50) | 1 (50) | |
| S (71) | 12 (16.9) | 59 (83.09) | 10 (14.08) | 61 (85.91) | 8 (11.26) | 63 (88.73) | |
|
| |||||||
| Cefepime | R (31) | 28 (90.32) | 3 (9.67) | 28 (90.32) | 3 (9.67) | 29 (93.54) | 2 (6.45) |
| I (5) | 5 (100) | - | 4 (80) | 1 (20) | 3 (60) | 2 (40) | |
| S (64) | 7 (10.93) | 57 (89.06) | 4 (6.25) | 60 (93.75) | 3 (4.68) | 61 (95.31) | |
|
| |||||||
| Imipenem | R (31) | 21 (67.74) | 10 (32.25) | 20 (64.51) | 11 (35.48) | 20 (64.51) | 11 (35.48) |
| I (8) | 4 (50) | 4 (50) | 4 (50) | 4 (50) | 4 (50) | 4 (50) | |
| S (61) | 15 (24.59) | 46 (75.4) | 12 (19.67) | 49 (80.32) | 11 (18.03) | 50 (81.96) | |
|
| |||||||
| Meropenem | R (37) | 27 (72.97) | 10 (27.02) | 25 (67.56) | 12 (32.43) | 26 (70.27) | 11 (29.72) |
| I (5) | 3 (60) | 2 (40) | 3 (60) | 2 (40) | 3 (60) | 2 (40) | |
| S (58) | 10 (17.24) | 48 (82.75) | 8 (13.79) | 50 (86.2) | 6 (10.34) | 52 (89.65) | |
|
| |||||||
| Doripenem | R (28) | 23 (82.14) | 5 (17.85) | 21 (75) | 7 (25) | 22 (78.57) | 6 (22.14) |
| I (11) | 6 (54.54) | 5 (45.45) | 6 (54.54) | 5 (45.45) | 6 (54.54) | 5 (45.45) | |
| S (61) | 11 (18.03) | 50 (81.96) | 9 (14.75) | 52 (85.24) | 8 (13.11) | 53 (86.88) | |
Abbreviations: R; resistant, I; intermediate resistant, S; susceptible