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. 2022 Jul 14;13:939175. doi: 10.3389/fgene.2022.939175

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Copyright © 2022 Zhou, Fang, Sun and Dong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Consensus clustering of the 3,168 m6A-related DEGs (A–D) Consensus matrices of the DGEs (k = 2–5) (E,F) Expression heatmap and histogram of the 3,168 m6A-related DEGs in gene cluster A and gene cluster B (G) The differential immune cell infiltration of DEGs in the two gene patterns (H) Principal component analysis for the expression profiles of gene subtypes, also shows a remarkable difference between different modification patterns. (I,J) Differences in m6A score based on PCA algorithm between the two m6A patterns or the two gene patterns. *p < 0.05, **p < 0.01, and ***p < 0.001.