TABLE 3.
Quality assessment of the included studies.
| Study (author, year) | (1) | (2) | (3) | (4) | (5) | (6) | (7) | (8) | (9) | (10) | Score |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Wohlgemuth et al. (2010) | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 6 | ||||
| Lin et al. (2013) | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 6 | ||||
| Luo et al. (2013) | ✓ | ✓ | ✓ | ✓ | ✓ | 5 | |||||
| Nalbandian et al. (2013) | ✓ | ✓ | Nk | ✓ | ✓ | 4 | |||||
| Zhao et al. (2013) | ✓ | ✓ | ✓ | Nk | 3 | ||||||
| Lee et al. (2015) | ✓ | ✓ | ✓ | Nk | ✓ | 4 | |||||
| Ziaaldini et al. (2015) | ✓ | ✓ | ✓ | ✓ | 4 | ||||||
| White et al. (2016) | ✓ | ✓ | ✓ | ✓ | ✓ | 5 | |||||
| Zhao et al. (2016) | ✓ | ✓ | ✓ | Nk | ✓ | 4 | |||||
| Ribeiro et al. (2017) | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 6 | ||||
| Bahreinipour et al. (2018) | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 6 | ||||
| Dethlefsen et al. (2018) | ✓ | ✓ | ✓ | ✓ | 4 | ||||||
| Zeng et al. (2020) | ✓ | ✓ | ✓ | Nk | ✓ | ✓ | ✓ | 6 | |||
| Liang et al. (2021) | ✓ | ✓ | ✓ | ✓ | ✓ | Nk | ✓ | ✓ | ✓ | 8 | |
| Zheng and Liang (2021) | ✓ | ✓ | Nk | ✓ | ✓ | 4 |
Note: studies fulfilling the criteria of the following: (1), peer reviewed publication; (2), control of temperature; (3), random allocation to treatment or control; (4), blinded induction of model; (5), blinded assessment of outcome; (6), use of anesthetic without significant intrinsic neuroprotective activity; (7), appropriate animal model (aged, diabetic, or hypertensive); (8), sample size calculation; (9), compliance with animal welfare regulations; and (10), statement of potential conflict of interests. Nk, not known.