Table 3.

Multivariate logistic regression analysis of sex for SA-AKI.

Model	OR (95%CI)	p-value
Model 1	1.129 (0.991-1.287)	0.068
Model 2	1.266 (1.100-1.457)	0.001
Model 3	1.230 (1.067-1.419)	0.004
Model 4	1.126 (0.943-1.344)	0.190
Model 5	1.137 (0.949-1.361)	0.163

Adjusted covariates: Model 1= sex (women=referent).

Model 2= Model 1 + age, BMI, ethnicity and admission type.

Model 3=Model 2 + comorbidities (hypertension, coronary atherosclerosis, heart failure, diabetes mellitus, COPD, cerebral infarction, chronic liver disease, chronic kidney disease, tumor).

Model 4=Model 3 + other variables with p<0.1 in the univariate analysis (APS III, OASIS, SOFA, MAP, temperature, WBC, platelet, PH, bicarbonate, BUN, creatinine, potassium, sodium, chloride, glucose, PT, APTT, lactate, vasopressor use, mechanical ventilation use, diuretic, aminoglycoside, statin, ACEI/ARBs).

Model 5 was adjusted for all baseline variables.

ACEI/ARBs, Angiotensin-converting enzyme inhibitors/angiotensin receptor blockers; APS III, Acute Physiology Score III; APTT, Activated partial thromboplastin time; BMI, Body mass index; BUN, Blood urea nitrogen; CI, Confidence interval; COPD, Chronic obstructive pulmonary disease; OASIS, Oxford Acute Severity of Illness Score; OR, Odds ratio; PT, Prothrombin time; SA-AKI, Sepsis associated acute kidney injury; SOFA, Sequential Organ Failure Assessment; RR, Respiratory rate; WBC, White blood cell.