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. 2022 Jul 24;10(8):1372. doi: 10.3390/healthcare10081372

Table 2.

Univariate analysis of risk factors for gallstone.

No Gallstone
(n = 2860)
Gallstone
(n = 178)
p-Value
Age, mean (SD) 55.1 (8.3) 57.4 (8.5) <0.001
Gender, no (%) 0.750
 Female 1178 (41.2) 76 (42.7)
 Male 1682 (58.8) 102 (57.3)
Waist circumference, cm, mean (SD) 85.4 (8.1) 87.1 (8.0) 0.007
SBP, no (%) 0.018
 ≥140 mmHg 335 (11.7) 32 (18.0)
 <140 mmHg 2525 (88.3) 146 (82.0)
Serum indices
 Hb, g/dL, mean (SD) 14.4 (1.5) 14.3 (1.6) 0.347
 Total bilirubin, mg/dL, mean (SD) 0.9 (0.4) 0.8 (0.3) 0.107
 Direct bilirubin, mg/dL, mean (SD) 0.3 (0.1) 0.3 (0.1) 0.166
 AST, IU/L, mean (SD) 25.8 (13.8) 26.4 (14.0) 0.583
 ALT, IU/L, mean (SD) 27.8 (18.2) 30.4 (32.5) 0.277
 γGTP, IU/L, mean (SD) 41.3 (52.4) 43.2 (61.6) 0.683
 ALP, IU/L, mean (SD) 65.3 (19.6) 66.8 (18.6) 0.333
 Total cholesterol, mg/dL, mean (SD) 190.6 (37.8) 187.8 (41.4) 0.334
 TG, mg/dL, mean (SD) 112.8 (76.6) 117.4 (64.3) 0.357
 HDL-C, mg/dL, mean (SD) 53.7 (15.9) 51.7 (15.6) 0.110
 LDL-C, mg/dL, mean (SD) 130.3 (35.0) 127.6 (38.7) 0.335
 FBG, mg/dL, mean (SD) 95.4 (22.4) 100.9 (26.0) 0.007
 HbA1c, no (%) <0.001
  ≥6.5 % 272 (9.5) 34 (19.1)
  <6.5% 2588 (90.5) 144 (80.9)
CCTA indices
 Sfat index, cm2/(kg/m2), mean (SD) 5.9 (2.0) 6.2 (2.1) 0.068
 Vfat index, cm2/(kg/m2), mean (SD) 4.5 (2.2) 4.9 (2.3) 0.018
 LAMA index, cm2/(kg/m2), mean (SD) 1.2 (3.8) 1.2 (0.3) 0.881
 NAMA index, cm2/(kg/m2), mean (SD) 4.5 (4.2) 4.2 (1.2) 0.015
Vigorous exercise, no (%) 0.015
 Less than 2 days in a week 1996 (69.8) 140 (78.7)
 2 or more days in a week 864 (30.2) 38 (21.3)
Univariate Analysis
OR (95% CI)  p-Values
Age, mean (SD) 1.04 (1.02–1.05) <0.001
Gender, no (%)
 Female 1
 Male 0.94 (0.69–1.28) 0.692
Waist circumference, cm, mean (SD) 1.02 (1.01–1.04) 0.007
SBP, no (%)
<140 mmHg 1
≥140 mmHg 1.65 (1.09–2.43) 0.014
Serum indices
 Hb, g/dL, mean (SD) 0.95 (0.87–1.05) 0.347
 Total bilirubin, mg/dL, mean (SD) 0.74 (0.48–1.10) 0.152
 Direct bilirubin, mg/dL, mean (SD) 0.40 (0.11–1.37) 0.162
 AST, IU/L, mean (SD) 1.00 (0.99–1.01) 0.583
 ALT, IU/L, mean (SD) 1.01 (1.00–1.01) 0.075
 γGTP, IU/L, mean (SD) 1.00 (1.00–1.00) 0.638
 ALP, IU/L, mean (SD) 1.00 (1.00–1.01) 0.332
 Total cholesterol, mg/dL, mean (SD) 1.00 (0.99–1.00) 0.334
 TG, mg/dL, mean (SD) 1.00 (1.00–1.00) 0.429
 HDL-C, mg/dL, mean (SD) 0.99 (0.98–1.00) 0.110
 LDL-C, mg/dL, mean (SD) 1.00 (0.99–1.00) 0.335
 FBG, mg/dL, mean (SD) 1.01 (1.00–1.01) 0.002
 HbA1c, no (%)
  <6.5% 1
  ≥6.5% 2.25 (1.49–3.29) <0.001
CCTA indices
 Sfat index, cm2/(kg/m2), mean (SD) 1.07 (0.99–1.15) 0.068
 Vfat index, cm2/(kg/m2), mean (SD) 1.08 (1.01–1.15) 0.018
 LAMA index, cm2/(kg/m2), mean (SD) 1.00 (1.00–1.02) 0.968
 NAMA index, cm2/(kg/m2), mean (SD) 0.86 (0.76–0.98) 0.021
Vigorous exercise, no (%)
 Less than 2 days in a week 1
 2 or more days in a week 0.63 (0.43–0.90) 0.013

SBP, systolic blood pressure; AST, aspartate aminotransferase; ALT, alanine aminotransferase; γGTP, gamma glutamyltransferase; ALP, alkaline phosphatase; FBG, fasting blood glucose; TG, triglyceride; HDL-C, high-density lipoprotein; LDL-C, low-density lipoprotein; CCTA, coronary CT angiography; Sfat, subcutaneous fat; Vfat, visceral fat; LAMA, low-attenuated muscle area; NAMA, normal-attenuated muscle area.