Table 3.

Novel potential circulating biomarkers for TAAD.

Marker	Animal Models	Human Cohort	TAA	TAAD
miR-1	-	aortic tissue specimens from ascending TAA patients (30)/3 tissues of patients with AAA, 11 tissues of patients with TAA and 8 controls [185,186]	+
miR-21			+
miR-29a			+	+
miR-133a			+	+
miR-15a	-	10 patients with TAA/3 tissue specimens from AAA patients, 11 from TAA patients and 8 controls/aortic tissue specimens from AAA patients (10) [186,187,188]	+	+
miR-22			+	+
miR-25			+
miR-29b			+
miR-125a-3p			+
miR-126-3p			+
miR-128			+
miR-133b			+	+
miR-138-1			+	+
miR-142–5p			+
miR-145			+	+
miR-146b-5p			+
miR-183			+	+
miR-422a			+
miR-433			+	+
miR-486–5p			+
miR-487b			+
miR-491–3p			+	+
miR-553			+	+
miR-638			+
miR-940			+	+
miR-193a-3p			+	+
miR-768–5p			+	+
miR-886–5p			+	+
miR-195			+	+
miR-140–5p			+	+
miR-30e			+	+
miR-101			+	+
miR-744			+	+
miR-193a-5p			+	+
miR-30c	-	3 tissues specimens from AAA patients, 11 from TAA patients and 8 controls [186]	+
miR-155			+
miR-204			+
miR-143	mouse models [183]	-	+	+

AAA: abdominal aortic aneurysm; miR: microRNA; TAA: aortic aneurysm, thoracic.