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. 2022 Jul 14;13:952413. doi: 10.3389/fimmu.2022.952413
EGR epigenetic regulator
LIHC liver hepatocellular carcinoma
HCC hepatocellular carcinoma
OS overall survival
CNAs copy number alterations
UVM uveal melanoma
TMB tumor mutational burden
MSI microsatellite instability
PDL-1 programmed cell death 1 ligand 1
TCGA The Cancer Genome Atlas
GEO Gene Expression Omnibus
ICGC International Cancer Genome Consortium
LGG brain lower grade glioma
KIRP kidney renal papillary cell carcinoma
KIRC kidney renal clear cell carcinoma
DEGs differentially expressed genes
FDR false discovery rate
LASSO least absolute shrinkage and selection operator
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
TRMT6 tRNA methyltransferase 6 non-catalytic subunit
YBX1 Y-box binding protein 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
SUV39H2 SUV39H2 histone lysine methyltransferase
YTHDF1 YTH N6-methyladenosine RNA binding protein 1
KEGG Kyoto Encyclopedia of Genes and Genomes
GSEA Gene Set Enrichment Analysis
ssGSEA single-sample gene set enrichment analysis
ROC receiver operating characteristic
AUC area under the curve
CTLA-4 cytotoxic T-lymphocyte associated protein 4
AFP alpha fetoprotein
DMGs differently methylated genes
Tregs regulatory T cells
DFS disease-free survival
EMT epithelial–mesenchymal transition
ABC transporter ATP-binding cassette transporter
SOX2 SRY-box transcription factor 2
OCT4 organic cation/carnitine transporter4
TACE transcatheter arterial chemoembolization
ICIs immune checkpoint inhibitors
ACT adoptive cell therapy
MHC major histocompatibility complex
TME tumor microenvironment
GSVA gene set variance analysis
CXCL9 C-X-C motif chemokine ligand 9
CXCL10 C-X-C motif chemokine ligand 10
CTCs circulating tumor cells
DDR DNA damage repair
MRE11 MRE11 homolog, double strand break repair nuclease
RAD50 RAD50 double strand break repair protein
NBN nibrin