EGR |
epigenetic regulator |
LIHC |
liver hepatocellular carcinoma |
HCC |
hepatocellular carcinoma |
OS |
overall survival |
CNAs |
copy number alterations |
UVM |
uveal melanoma |
TMB |
tumor mutational burden |
MSI |
microsatellite instability |
PDL-1 |
programmed cell death 1 ligand 1 |
TCGA |
The Cancer Genome Atlas |
GEO |
Gene Expression Omnibus |
ICGC |
International Cancer Genome Consortium |
LGG |
brain lower grade glioma |
KIRP |
kidney renal papillary cell carcinoma |
KIRC |
kidney renal clear cell carcinoma |
DEGs |
differentially expressed genes |
FDR |
false discovery rate |
LASSO |
least absolute shrinkage and selection operator |
EZH2 |
enhancer of zeste 2 polycomb repressive complex 2 subunit |
TRMT6 |
tRNA methyltransferase 6 non-catalytic subunit |
YBX1 |
Y-box binding protein 1 |
IGF2BP3 |
insulin-like growth factor 2 mRNA binding protein 3 |
SUV39H2 |
SUV39H2 histone lysine methyltransferase |
YTHDF1 |
YTH N6-methyladenosine RNA binding protein 1 |
KEGG |
Kyoto Encyclopedia of Genes and Genomes |
GSEA |
Gene Set Enrichment Analysis |
ssGSEA |
single-sample gene set enrichment analysis |
ROC |
receiver operating characteristic |
AUC |
area under the curve |
CTLA-4 |
cytotoxic T-lymphocyte associated protein 4 |
AFP |
alpha fetoprotein |
DMGs |
differently methylated genes |
Tregs |
regulatory T cells |
DFS |
disease-free survival |
EMT |
epithelial–mesenchymal transition |
ABC transporter |
ATP-binding cassette transporter |
SOX2 |
SRY-box transcription factor 2 |
OCT4 |
organic cation/carnitine transporter4 |
TACE |
transcatheter arterial chemoembolization |
ICIs |
immune checkpoint inhibitors |
ACT |
adoptive cell therapy |
MHC |
major histocompatibility complex |
TME |
tumor microenvironment |
GSVA |
gene set variance analysis |
CXCL9 |
C-X-C motif chemokine ligand 9 |
CXCL10 |
C-X-C motif chemokine ligand 10 |
CTCs |
circulating tumor cells |
DDR |
DNA damage repair |
MRE11 |
MRE11 homolog, double strand break repair nuclease |
RAD50 |
RAD50 double strand break repair protein |
NBN |
nibrin |