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| formulation | size (d. nm) | PDI | zeta-potential (mV) | pH | % EE |
|---|---|---|---|---|---|
| Placebo | |||||
| PPADT | 220 ± 4 | 0.09 ± 0.02 | –1.45 ± 0.1 | 7.2 ± 0.1 | |
| PLGA | 243 ± 2 | 0.12 ± 0.01 | –0.76 ± 0.7 | 7.1 ± 0.3 | |
| NR | |||||
| PPADT | 246 ± 3 | 0.09 ± 0.02 | –1.53 ± 1 | 7.2 ± 0.1 | 9.4 ± 2.5 |
| PLGA | 302 ± 3 | 0.11 ± 0.01 | –0.51 ± 0.4 | 7.1 ± 0.5 | 10.7 ± 1.9 |
The encapsulation efficiency (% EE) for NR-loaded nanoparticles is indicated in the column to the right.
