Table 2.
Aberrantly expressed lncRNAs associated with the brain-heart axis and inflammation after SARS-CoV-2 infection.
| ncRNA | Type of sample | Regulation | Pathways related to COVID-19 | Reference | |
|---|---|---|---|---|---|
| Brain-heart | DANCR | Lung tissue, brain | ↑ | mTOR | [31] |
| NEAT1 | Lung tissue, brain, PBMCs, HUVECs | ↓ | RUNX3, SPI1 | [31], [32], [33], [34] | |
| MALAT1 | PBMCs | ↓ | – | [32], [33] | |
| Inflammation | SNGH25 | PBMCs | ↓ | – | [32] |
| AC010904.2 | PBMCs | ↑ | – | [35] | |
| AC012065.4 | |||||
| AL365203.2 | |||||
| AC010175.1 | |||||
| LINC00562 | |||||
| AC010536.1 | |||||
| AP005671.1 | |||||
| SNHG1 | PBMCs | ↑ | IL-7 | [36] |
Up and down arrows, indicate an increase and decrease of expression with increasing disease severity, respectively. PBMCs – peripheral blood mononuclear cells.