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. 2022 Jul 23;10(8):1779. doi: 10.3390/biomedicines10081779

Figure 5.

Figure 5

Serum CCL4 levels as a biomarker of type 2 airway inflammation. (A–F) FENO (A), serum total IgE (B), CCL4 (C), CCL11 (D), CCL26 (E), and CCL17 (F) levels were evaluated pre- and post-treatment with Dupilumab. Individual values are shown (n = 19); # p < 0.05, ## p < 0.01 (vs. pre-treatment). (G,H) Correlations between serum CCL4 levels and FENO (G) or total serum IgE levels (H). (I) Correlations between serum CCL11/CCL26/CCL17 levels and FENO or total serum IgE levels. (J) Correlations between serum CCL4 and CCL17 levels. Individual values are shown (n = 77: samples from patients with severe ECRS and asthma who received any biotherapy).