Table 2.
Clinical and laboratory characteristics of participants based on tertiles of MHR (108/mmol).
| Variable | T1 (<3.12) | T2 (3.12-4.57) | T3 (>4.57) | P |
|---|---|---|---|---|
| Age (year) | 53.0 ± 7.5 | 53.2 ± 7.9 | 54.1± 7.3 | 0.33 |
| Men, n (%) | 100 (49.5) | 102 (50.0) | 102 (51.3) | 0.937 |
| BMI (kg/m2) | 22.3 ± 2.2ab | 24.4 ± 2.2ac | 26.3 ± 3.0bc | < 0.001 |
| HbA1c (%) | 9.1 ± 1.2 | 8.9 ± 1.0 | 9.0 ± 1.1 | 0.314 |
| WC (cm) | 81.1 ± 4.3ab | 85.5 ± 5.1ac | 90.5± 7.4bc | < 0.001 |
| TG (mmol/L) | 1.26 ± 0.89ab | 1.89 ± 0.71ac | 3.30± 1.51bc | < 0.001 |
| HDL-c (mmol/L) | 1.30 ± 0.21ab | 1.06 ± 0.17ac | 0.93 ± 0.20bc | < 0.001 |
| LDL-c (mmol/L) | 3.38 ± 0.88 | 3.55 ± 0.90 | 3.50 ± 0.93 | 0.156 |
| ApoA1 (g/L) | 1.09 ± 0.22ab | 1.04 ± 0.19ac | 0.96 ± 0.21bc | < 0.001 |
| Monocyte (109/L) | 0.32 ± 0.06ab | 0.41 ± 0.05ac | 0.51 ± 0.08bc | < 0.001 |
| UA (umol/L) | 298.8 ± 71.7ab | 357.2 ± 64.7ac | 402.8 ± 85.1bc | < 0.001 |
| Creatinine (umol/L) | 71.6 ± 13.3 | 70.7 ± 13.9 | 69.2 ± 12.2 | 0.185 |
| ALT (IU/L) | 35.7 ± 9.9 | 34.0 ± 7.0 | 35.4 ± 9.9 | 0.108 |
| SBP (mmHg) | 119.3 ± 13.0ab | 131.6 ± 15.7ac | 146.5 ± 10.9bc | < 0.001 |
| DBP (mmHg) | 77.0 ± 6.1ab | 79.7 ± 10.9ac | 87.9 ± 7.8bc | < 0.001 |
| Insulin (mU/ml) | 16.9 ± 8.1ab | 26.4 ± 9.8ac | 34.5 ± 10.3bc | < 0.001 |
| HOMA-IR | 7.2 ± 5.3ab | 11.1 ± 4.5ac | 14.1 ± 6.0bc | < 0.001 |
| hs-CRP (mg/L) | 2.9 ± 0.9 | 3.0 ± 1.0 | 3.1 ± 0.9 | 0.373 |
| Hypertension, n (%) | 28 (13.9)ab | 56 (27.5)ac | 131 (65.8)bc | < 0.001 |
| Smoking,n (%) | 66 (32.7) | 75 (36.8) | 77 (38.6) | 0.439 |
| Drinking,n (%) | 72 (35.6) | 74 (36.3) | 78 (39.2) | 0.735 |
| MAR (108/g) | 3.07 ± 0.86ab | 4.03 ± 0.77ac | 5.67 ± 1.97bc | < 0.001 |
| MetS, n (%) | 60 (29.7)ab | 128 (62.7)ac | 176 (88.4)bc | < 0.001 |
BMI, body mass index; UA, uric acid; TG, triglyceride; HDL-c, high-density lipoprotein cholesterol; LDL-c, low-density lipoprotein cholesterol; ApoA1, apolipoprotein A1; SBP, systolic blood pressure; DBP, diastolic blood pressure; HOMR-IR, homeostasis model assessment insulin resistance; hs-CRP, high-sensitivity C-reactive protein; MHR, monocyte–to–HDL-c ratio; MAR, monocyte-to-ApoA1 ratio. aP < 0.05: T1 vs. T2. bP < 0.05: T1 vs. T3. cP < 0.05: T2 vs. T3.